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The “child size medicines” concept: policy provisions in Uganda

BACKGROUND: In 2007, the World Health Organization (WHO) launched the ‘make medicines child size’ (MMCS) campaign by urging countries to prioritize procurement of medicines with appropriate strengths for children’s age and weight and, in child-friendly formulations of rectal and flexible oral solid...

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Autores principales: Nsabagasani, Xavier, Ogwal-Okeng, Jasper, Mbonye, Anthony, Ssengooba, Freddie, Nantanda, Rebecca, Muyinda, Herbert, Holme Hansen, Ebba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342089/
https://www.ncbi.nlm.nih.gov/pubmed/25815197
http://dx.doi.org/10.1186/s40545-015-0025-7
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author Nsabagasani, Xavier
Ogwal-Okeng, Jasper
Mbonye, Anthony
Ssengooba, Freddie
Nantanda, Rebecca
Muyinda, Herbert
Holme Hansen, Ebba
author_facet Nsabagasani, Xavier
Ogwal-Okeng, Jasper
Mbonye, Anthony
Ssengooba, Freddie
Nantanda, Rebecca
Muyinda, Herbert
Holme Hansen, Ebba
author_sort Nsabagasani, Xavier
collection PubMed
description BACKGROUND: In 2007, the World Health Organization (WHO) launched the ‘make medicines child size’ (MMCS) campaign by urging countries to prioritize procurement of medicines with appropriate strengths for children’s age and weight and, in child-friendly formulations of rectal and flexible oral solid formulations. This study examined policy provisions for MMCS recommendations in Uganda. METHODS: This was an in-depth case study of the Ugandan health policy documents to assess provisions for MMCS recommendations in respect to oral and rectal medicine formulations for malaria, pneumonia and diarrhea, the major causes of morbidity and mortality among children in Uganda- diseases that were also emphasized in the MMCS campaign. Asthma and epilepsy were included as conditions that require long term care. Schistomiasis was included as a neglected tropical disease. Content analysis was used to assess evidence of policy provisions for the MMCS recommendations. RESULTS: For most medicines for the selected diseases, appropriate strength for children’s age and weight was addressed especially in the EMHSLU 2012. However, policy documents neither referred to ‘child size medicines’ concept nor provided for flexible oral solid dosage formulations like dispersible tablets, pellets and granules- indicating limited adherence to MMCS recommendations. Some of the medicines recommended in the clinical guidelines as first line treatment for malaria and pneumonia among children were not evidence-based. CONCLUSION: The Ugandan health policy documents reflected limited adherence to the MMCS recommendations. This and failure to use evidence based medicines may result into treatment failure and or death. A revision of the current policies and guidelines to better reflect ‘child size’, child appropriate and evidence based medicines for children is recommended.
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spelling pubmed-43420892015-03-26 The “child size medicines” concept: policy provisions in Uganda Nsabagasani, Xavier Ogwal-Okeng, Jasper Mbonye, Anthony Ssengooba, Freddie Nantanda, Rebecca Muyinda, Herbert Holme Hansen, Ebba J Pharm Policy Pract Research Article BACKGROUND: In 2007, the World Health Organization (WHO) launched the ‘make medicines child size’ (MMCS) campaign by urging countries to prioritize procurement of medicines with appropriate strengths for children’s age and weight and, in child-friendly formulations of rectal and flexible oral solid formulations. This study examined policy provisions for MMCS recommendations in Uganda. METHODS: This was an in-depth case study of the Ugandan health policy documents to assess provisions for MMCS recommendations in respect to oral and rectal medicine formulations for malaria, pneumonia and diarrhea, the major causes of morbidity and mortality among children in Uganda- diseases that were also emphasized in the MMCS campaign. Asthma and epilepsy were included as conditions that require long term care. Schistomiasis was included as a neglected tropical disease. Content analysis was used to assess evidence of policy provisions for the MMCS recommendations. RESULTS: For most medicines for the selected diseases, appropriate strength for children’s age and weight was addressed especially in the EMHSLU 2012. However, policy documents neither referred to ‘child size medicines’ concept nor provided for flexible oral solid dosage formulations like dispersible tablets, pellets and granules- indicating limited adherence to MMCS recommendations. Some of the medicines recommended in the clinical guidelines as first line treatment for malaria and pneumonia among children were not evidence-based. CONCLUSION: The Ugandan health policy documents reflected limited adherence to the MMCS recommendations. This and failure to use evidence based medicines may result into treatment failure and or death. A revision of the current policies and guidelines to better reflect ‘child size’, child appropriate and evidence based medicines for children is recommended. BioMed Central 2015-01-31 /pmc/articles/PMC4342089/ /pubmed/25815197 http://dx.doi.org/10.1186/s40545-015-0025-7 Text en © Nsabagasani et al.; licensee BioMed Central. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Nsabagasani, Xavier
Ogwal-Okeng, Jasper
Mbonye, Anthony
Ssengooba, Freddie
Nantanda, Rebecca
Muyinda, Herbert
Holme Hansen, Ebba
The “child size medicines” concept: policy provisions in Uganda
title The “child size medicines” concept: policy provisions in Uganda
title_full The “child size medicines” concept: policy provisions in Uganda
title_fullStr The “child size medicines” concept: policy provisions in Uganda
title_full_unstemmed The “child size medicines” concept: policy provisions in Uganda
title_short The “child size medicines” concept: policy provisions in Uganda
title_sort “child size medicines” concept: policy provisions in uganda
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342089/
https://www.ncbi.nlm.nih.gov/pubmed/25815197
http://dx.doi.org/10.1186/s40545-015-0025-7
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