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Fan-Shaped Complete Block on Helical Tomotherapy for Esophageal Cancer: A Phantom Study
Radiation pneumonitis (RP) is a common complication for radiotherapy of esophageal cancer and is associated with the low dose irradiated lung volume. This study aims to reduce the mean lung dose (MLD) and the relative lung volume at 20 Gy (V (20)) and at low dose region using various designs of the...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342177/ https://www.ncbi.nlm.nih.gov/pubmed/25767810 http://dx.doi.org/10.1155/2015/959504 |
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author | Chang, Chiu-Han Mok, Greta S. P. Shueng, Pei-Wei Yeh, Hsin-Pei Shiau, An-Cheng Tien, Hui-Ju Lin, Chi-Ta Wu, Tung-Hsin |
author_facet | Chang, Chiu-Han Mok, Greta S. P. Shueng, Pei-Wei Yeh, Hsin-Pei Shiau, An-Cheng Tien, Hui-Ju Lin, Chi-Ta Wu, Tung-Hsin |
author_sort | Chang, Chiu-Han |
collection | PubMed |
description | Radiation pneumonitis (RP) is a common complication for radiotherapy of esophageal cancer and is associated with the low dose irradiated lung volume. This study aims to reduce the mean lung dose (MLD) and the relative lung volume at 20 Gy (V (20)) and at low dose region using various designs of the fan-shaped complete block (FSCB) in helical tomotherapy. Hypothetical esophageal tumor was delineated on an anthropomorphic phantom. The FSCB was defined as the fan-shaped radiation restricted area located in both lungs. Seven treatment plans were performed with nonblock design and FSCB with different fan angles, that is, from 90° to 140°, with increment of 10°. The homogeneous index, conformation number, MLD, and the relative lung volume receiving more than 5, 10, 15, and 20 Gy (V (5), V (10), V (15), and V (20)) were determined for each treatment scheme. There was a substantial reduction in the MLD, V (5), V (10), V (15), and V (20) when using different types of FSCB as compared to the nonblock design. The reduction of V (20), V (15), V (10), and V (5) was 6.3%–8.6%, 16%–23%, 42%–57%, and 42%–66% for FSCB 90°–140°, respectively. The use of FSCB in helical tomotherapy is a promising method to reduce the MLD, V (20), and relative lung volume in low dose region, especially in V (5) and V (10) for esophageal cancer. |
format | Online Article Text |
id | pubmed-4342177 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-43421772015-03-12 Fan-Shaped Complete Block on Helical Tomotherapy for Esophageal Cancer: A Phantom Study Chang, Chiu-Han Mok, Greta S. P. Shueng, Pei-Wei Yeh, Hsin-Pei Shiau, An-Cheng Tien, Hui-Ju Lin, Chi-Ta Wu, Tung-Hsin Biomed Res Int Research Article Radiation pneumonitis (RP) is a common complication for radiotherapy of esophageal cancer and is associated with the low dose irradiated lung volume. This study aims to reduce the mean lung dose (MLD) and the relative lung volume at 20 Gy (V (20)) and at low dose region using various designs of the fan-shaped complete block (FSCB) in helical tomotherapy. Hypothetical esophageal tumor was delineated on an anthropomorphic phantom. The FSCB was defined as the fan-shaped radiation restricted area located in both lungs. Seven treatment plans were performed with nonblock design and FSCB with different fan angles, that is, from 90° to 140°, with increment of 10°. The homogeneous index, conformation number, MLD, and the relative lung volume receiving more than 5, 10, 15, and 20 Gy (V (5), V (10), V (15), and V (20)) were determined for each treatment scheme. There was a substantial reduction in the MLD, V (5), V (10), V (15), and V (20) when using different types of FSCB as compared to the nonblock design. The reduction of V (20), V (15), V (10), and V (5) was 6.3%–8.6%, 16%–23%, 42%–57%, and 42%–66% for FSCB 90°–140°, respectively. The use of FSCB in helical tomotherapy is a promising method to reduce the MLD, V (20), and relative lung volume in low dose region, especially in V (5) and V (10) for esophageal cancer. Hindawi Publishing Corporation 2015 2015-02-12 /pmc/articles/PMC4342177/ /pubmed/25767810 http://dx.doi.org/10.1155/2015/959504 Text en Copyright © 2015 Chiu-Han Chang et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Chang, Chiu-Han Mok, Greta S. P. Shueng, Pei-Wei Yeh, Hsin-Pei Shiau, An-Cheng Tien, Hui-Ju Lin, Chi-Ta Wu, Tung-Hsin Fan-Shaped Complete Block on Helical Tomotherapy for Esophageal Cancer: A Phantom Study |
title | Fan-Shaped Complete Block on Helical Tomotherapy for Esophageal Cancer: A Phantom Study |
title_full | Fan-Shaped Complete Block on Helical Tomotherapy for Esophageal Cancer: A Phantom Study |
title_fullStr | Fan-Shaped Complete Block on Helical Tomotherapy for Esophageal Cancer: A Phantom Study |
title_full_unstemmed | Fan-Shaped Complete Block on Helical Tomotherapy for Esophageal Cancer: A Phantom Study |
title_short | Fan-Shaped Complete Block on Helical Tomotherapy for Esophageal Cancer: A Phantom Study |
title_sort | fan-shaped complete block on helical tomotherapy for esophageal cancer: a phantom study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342177/ https://www.ncbi.nlm.nih.gov/pubmed/25767810 http://dx.doi.org/10.1155/2015/959504 |
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