Exome sequencing of a family with lone, autosomal dominant atrial flutter identifies a rare variation in ABCB4 significantly enriched in cases

BACKGROUND: Lone atrial flutter (AFL) and atrial fibrillation (AF) are common and sometimes consequential cardiac conduction disorders with a strong heritability, as underlined by recent genome-wide association studies that identified genetic modifiers. Follow-up family-based genetic analysis also i...

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Detalles Bibliográficos
Autores principales: Maciąg, Anna, Villa, Francesco, Ferrario, Anna, Spinelli, Chiara Carmela, Carrizzo, Albino, Malovini, Alberto, Torella, Annalaura, Montenero, Chiara, Parisi, Attilio, Condorelli, Gianluigi, Vecchione, Carmine, Nigro, Vincenzo, Montenero, Annibale Sandro, Puca, Annibale Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342200/
https://www.ncbi.nlm.nih.gov/pubmed/25888430
http://dx.doi.org/10.1186/s12863-015-0177-0

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