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Immunogenicity and Protective Efficacy of a Vero Cell Culture-Derived Whole-Virus H7N9 Vaccine in Mice and Guinea Pigs

BACKGROUND: A novel avian H7N9 virus with a high case fatality rate in humans emerged in China in 2013. We evaluated the immunogenicity and protective efficacy of a candidate Vero cell culture-derived whole-virus H7N9 vaccine in small animal models. METHODS: Antibody responses induced in immunized D...

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Detalles Bibliográficos
Autores principales:	Wodal, Walter, Schwendinger, Michael G., Savidis-Dacho, Helga, Crowe, Brian A., Hohenadl, Christine, Fritz, Richard, Brühl, Peter, Portsmouth, Daniel, Karner-Pichl, Anita, Balta, Dalida, Grillberger, Leopold, Kistner, Otfried, Barrett, P. Noel, Howard, M. Keith
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342221/ https://www.ncbi.nlm.nih.gov/pubmed/25719901 http://dx.doi.org/10.1371/journal.pone.0113963

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