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Carboxyl-Terminal Truncations Alter the Activity of the Human α-Galactosidase A

Fabry disease is an X-linked inborn error of glycolipid metabolism caused by deficiency of the human lysosomal enzyme, α-galactosidase A (αGal), leading to strokes, myocardial infarctions, and terminal renal failure, often leading to death in the fourth or fifth decade of life. The enzyme is respons...

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Detalles Bibliográficos
Autores principales:	Meghdari, Mariam, Gao, Nicholas, Abdullahi, Abass, Stokes, Erin, Calhoun, David H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342250/ https://www.ncbi.nlm.nih.gov/pubmed/25719393 http://dx.doi.org/10.1371/journal.pone.0118341

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