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Myelin Abnormalities in the Optic and Sciatic Nerves in Mice With GM1-Gangliosidosis

GM1-gangliosidosis is a glycosphingolipid lysosomal storage disease involving accumulation of GM1 and its asialo form (GA1) primarily in the brain. Thin-layer chromatography and X-ray diffraction were used to analyze the lipid content/composition and the myelin structure of the optic and sciatic ner...

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Detalles Bibliográficos
Autores principales: Heinecke, Karie A., Luoma, Adrienne, d’Azzo, Alessandra, Kirschner, Daniel A., Seyfried, Thomas N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342369/
https://www.ncbi.nlm.nih.gov/pubmed/25694553
http://dx.doi.org/10.1177/1759091415568913

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