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Myelin Abnormalities in the Optic and Sciatic Nerves in Mice With GM1-Gangliosidosis
GM1-gangliosidosis is a glycosphingolipid lysosomal storage disease involving accumulation of GM1 and its asialo form (GA1) primarily in the brain. Thin-layer chromatography and X-ray diffraction were used to analyze the lipid content/composition and the myelin structure of the optic and sciatic ner...
Autores principales: | Heinecke, Karie A., Luoma, Adrienne, d’Azzo, Alessandra, Kirschner, Daniel A., Seyfried, Thomas N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342369/ https://www.ncbi.nlm.nih.gov/pubmed/25694553 http://dx.doi.org/10.1177/1759091415568913 |
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