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The role of microtubule-associated protein 1B in axonal growth and neuronal migration in the central nervous system☆

In this review, we discuss the role of microtubule-associated protein 1B (MAP1B) and its phosphorylation in axonal development and regeneration in the central nervous system. MAP1B exhibits similar functions during axonal development and regeneration. MAP1B and phosphorylated MAP1B in neurons and ax...

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Detalles Bibliográficos
Autores principales: Yang, Maoguang, Wu, Minfei, Xia, Peng, Wang, Chunxin, Yan, Peng, Gao, Qi, Liu, Jian, Wang, Haitao, Duan, Xingwei, Yang, Xiaoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342712/
https://www.ncbi.nlm.nih.gov/pubmed/25737712
http://dx.doi.org/10.3969/j.issn.1673-5374.2012.11.008
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author Yang, Maoguang
Wu, Minfei
Xia, Peng
Wang, Chunxin
Yan, Peng
Gao, Qi
Liu, Jian
Wang, Haitao
Duan, Xingwei
Yang, Xiaoyu
author_facet Yang, Maoguang
Wu, Minfei
Xia, Peng
Wang, Chunxin
Yan, Peng
Gao, Qi
Liu, Jian
Wang, Haitao
Duan, Xingwei
Yang, Xiaoyu
author_sort Yang, Maoguang
collection PubMed
description In this review, we discuss the role of microtubule-associated protein 1B (MAP1B) and its phosphorylation in axonal development and regeneration in the central nervous system. MAP1B exhibits similar functions during axonal development and regeneration. MAP1B and phosphorylated MAP1B in neurons and axons maintain a dynamic balance between cytoskeletal components, and regulate the stability and interaction of microtubules and actin to promote axonal growth, neural connectivity and regeneration in the central nervous system.
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spelling pubmed-43427122015-03-03 The role of microtubule-associated protein 1B in axonal growth and neuronal migration in the central nervous system☆ Yang, Maoguang Wu, Minfei Xia, Peng Wang, Chunxin Yan, Peng Gao, Qi Liu, Jian Wang, Haitao Duan, Xingwei Yang, Xiaoyu Neural Regen Res Review In this review, we discuss the role of microtubule-associated protein 1B (MAP1B) and its phosphorylation in axonal development and regeneration in the central nervous system. MAP1B exhibits similar functions during axonal development and regeneration. MAP1B and phosphorylated MAP1B in neurons and axons maintain a dynamic balance between cytoskeletal components, and regulate the stability and interaction of microtubules and actin to promote axonal growth, neural connectivity and regeneration in the central nervous system. Medknow Publications & Media Pvt Ltd 2012-04-15 /pmc/articles/PMC4342712/ /pubmed/25737712 http://dx.doi.org/10.3969/j.issn.1673-5374.2012.11.008 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Yang, Maoguang
Wu, Minfei
Xia, Peng
Wang, Chunxin
Yan, Peng
Gao, Qi
Liu, Jian
Wang, Haitao
Duan, Xingwei
Yang, Xiaoyu
The role of microtubule-associated protein 1B in axonal growth and neuronal migration in the central nervous system☆
title The role of microtubule-associated protein 1B in axonal growth and neuronal migration in the central nervous system☆
title_full The role of microtubule-associated protein 1B in axonal growth and neuronal migration in the central nervous system☆
title_fullStr The role of microtubule-associated protein 1B in axonal growth and neuronal migration in the central nervous system☆
title_full_unstemmed The role of microtubule-associated protein 1B in axonal growth and neuronal migration in the central nervous system☆
title_short The role of microtubule-associated protein 1B in axonal growth and neuronal migration in the central nervous system☆
title_sort role of microtubule-associated protein 1b in axonal growth and neuronal migration in the central nervous system☆
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342712/
https://www.ncbi.nlm.nih.gov/pubmed/25737712
http://dx.doi.org/10.3969/j.issn.1673-5374.2012.11.008
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