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The role of microtubule-associated protein 1B in axonal growth and neuronal migration in the central nervous system☆
In this review, we discuss the role of microtubule-associated protein 1B (MAP1B) and its phosphorylation in axonal development and regeneration in the central nervous system. MAP1B exhibits similar functions during axonal development and regeneration. MAP1B and phosphorylated MAP1B in neurons and ax...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342712/ https://www.ncbi.nlm.nih.gov/pubmed/25737712 http://dx.doi.org/10.3969/j.issn.1673-5374.2012.11.008 |
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author | Yang, Maoguang Wu, Minfei Xia, Peng Wang, Chunxin Yan, Peng Gao, Qi Liu, Jian Wang, Haitao Duan, Xingwei Yang, Xiaoyu |
author_facet | Yang, Maoguang Wu, Minfei Xia, Peng Wang, Chunxin Yan, Peng Gao, Qi Liu, Jian Wang, Haitao Duan, Xingwei Yang, Xiaoyu |
author_sort | Yang, Maoguang |
collection | PubMed |
description | In this review, we discuss the role of microtubule-associated protein 1B (MAP1B) and its phosphorylation in axonal development and regeneration in the central nervous system. MAP1B exhibits similar functions during axonal development and regeneration. MAP1B and phosphorylated MAP1B in neurons and axons maintain a dynamic balance between cytoskeletal components, and regulate the stability and interaction of microtubules and actin to promote axonal growth, neural connectivity and regeneration in the central nervous system. |
format | Online Article Text |
id | pubmed-4342712 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-43427122015-03-03 The role of microtubule-associated protein 1B in axonal growth and neuronal migration in the central nervous system☆ Yang, Maoguang Wu, Minfei Xia, Peng Wang, Chunxin Yan, Peng Gao, Qi Liu, Jian Wang, Haitao Duan, Xingwei Yang, Xiaoyu Neural Regen Res Review In this review, we discuss the role of microtubule-associated protein 1B (MAP1B) and its phosphorylation in axonal development and regeneration in the central nervous system. MAP1B exhibits similar functions during axonal development and regeneration. MAP1B and phosphorylated MAP1B in neurons and axons maintain a dynamic balance between cytoskeletal components, and regulate the stability and interaction of microtubules and actin to promote axonal growth, neural connectivity and regeneration in the central nervous system. Medknow Publications & Media Pvt Ltd 2012-04-15 /pmc/articles/PMC4342712/ /pubmed/25737712 http://dx.doi.org/10.3969/j.issn.1673-5374.2012.11.008 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Yang, Maoguang Wu, Minfei Xia, Peng Wang, Chunxin Yan, Peng Gao, Qi Liu, Jian Wang, Haitao Duan, Xingwei Yang, Xiaoyu The role of microtubule-associated protein 1B in axonal growth and neuronal migration in the central nervous system☆ |
title | The role of microtubule-associated protein 1B in axonal growth and neuronal migration in the central nervous system☆ |
title_full | The role of microtubule-associated protein 1B in axonal growth and neuronal migration in the central nervous system☆ |
title_fullStr | The role of microtubule-associated protein 1B in axonal growth and neuronal migration in the central nervous system☆ |
title_full_unstemmed | The role of microtubule-associated protein 1B in axonal growth and neuronal migration in the central nervous system☆ |
title_short | The role of microtubule-associated protein 1B in axonal growth and neuronal migration in the central nervous system☆ |
title_sort | role of microtubule-associated protein 1b in axonal growth and neuronal migration in the central nervous system☆ |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342712/ https://www.ncbi.nlm.nih.gov/pubmed/25737712 http://dx.doi.org/10.3969/j.issn.1673-5374.2012.11.008 |
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