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Characterization of the differences in the cyclopiazonic acid binding mode to mammalian and P. Falciparum Ca(2+) pumps: A computational study
Despite the investments in malaria research, an effective vaccine has not yet been developed and the causative parasites are becoming increasingly resistant to most of the available drugs. PfATP6, the sarco/endoplasmic reticulum Ca2+ pump (SERCA) of P. falciparum, has been recently genetically valid...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342768/ https://www.ncbi.nlm.nih.gov/pubmed/25581715 http://dx.doi.org/10.1002/prot.24734 |