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One-Pot, Three-Component Arylalkynyl Sulfone Synthesis
[Image: see text] A one-pot three-component protocol for the preparation of arylsulfonyl alkynes through the reaction of ethynyl-benziodoxolone (EBX) reagents, DABSO (DABCO·SO(2)), and either organomagnesium reagents or aryl iodides with a palladium catalyst is reported. A broad range of aryl and he...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342956/ https://www.ncbi.nlm.nih.gov/pubmed/25633719 http://dx.doi.org/10.1021/acs.orglett.5b00015 |
| Sumario: | [Image: see text] A one-pot three-component protocol for the preparation of arylsulfonyl alkynes through the reaction of ethynyl-benziodoxolone (EBX) reagents, DABSO (DABCO·SO(2)), and either organomagnesium reagents or aryl iodides with a palladium catalyst is reported. A broad range of aryl and heteroarylalkynyl sulfones were obtained in 46–85% overall yield. |
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