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Estriol preserves synaptic transmission in the hippocampus during autoimmune demyelinating disease

Cognitive deficits occur in over half of multiple sclerosis patients, with hippocampal-dependent learning and memory commonly impaired. Data from in vivo MRI and post-mortem studies in MS indicate that the hippocampus is targeted. However the relationship between structural pathology and dysfunction...

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Detalles Bibliográficos
Autores principales: Ziehn, Marina O., Avedisian, Andrea A., Dervin, Shannon M., O’Dell, Thomas J., Voskuhl, Rhonda R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4343001/
https://www.ncbi.nlm.nih.gov/pubmed/22525427
http://dx.doi.org/10.1038/labinvest.2012.76