Interleukin-1 loop model for pathogenesis of Langerhans cell histiocytosis

We propose Langerhans cell histiocytosis (LCH) is an inflammatory process that is prolonged by mutations. We hypothesize that Merkel cell polyomavirus (MCPyV) infection triggers an interleukin-1 (IL-1) activation loop that underlies the pathogenesis of LCH. Langerhans cells (LCs) are antigen present...

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Detalles Bibliográficos
Autores principales: Murakami, Ichiro, Matsushita, Michiko, Iwasaki, Takeshi, Kuwamoto, Satoshi, Kato, Masako, Nagata, Keiko, Horie, Yasushi, Hayashi, Kazuhiko, Imamura, Toshihiko, Morimoto, Akira, Imashuku, Shinsaku, Gogusev, Jean, Jaubert, Francis, Takata, Katsuyoshi, Oka, Takashi, Yoshino, Tadashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4343072/
https://www.ncbi.nlm.nih.gov/pubmed/25889448
http://dx.doi.org/10.1186/s12964-015-0092-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4343072/
https://www.ncbi.nlm.nih.gov/pubmed/25889448
http://dx.doi.org/10.1186/s12964-015-0092-z

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