Single live cell TGF-β signalling imaging: breast cancer cell motility and migration is driven by sub-populations of cells with dynamic TGF-β-Smad3 activity

BACKGROUND: Metastasis is a process where only a small subset of cells is capable of successfully migrating to and propagating at secondary sites. TGF-β signalling is widely known for its role in cancer metastasis and is associated with cell migration in whole cell populations. FINDINGS: We extend t...

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Detalles Bibliográficos
Autores principales: Luwor, Rodney B, Hakmana, Dulani, Iaria, Josephine, Nheu, Thao V, Simpson, Richard J, Zhu, Hong-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4343191/
https://www.ncbi.nlm.nih.gov/pubmed/25744371
http://dx.doi.org/10.1186/s12943-015-0309-1

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