Regulatory iNKT cells lack PLZF expression and control T(reg) cell and macrophage homeostasis in adipose tissue

iNKT cells are CD1d-restricted lipid-sensing innate T cells that express the transcription factor PLZF. iNKT cells accumulate in adipose tissue, where they are anti-inflammatory, but the factors that contribute to their anti-inflammatory nature, and their targets in adipose tissue are unknown. Here...

Descripción completa

Detalles Bibliográficos
Autores principales: Lynch, Lydia, Michelet, Xavier, Zhang, Sai, Brennan, Patrick J., Moseman, Ashley, Lester, Chantel, Besra, Gurdyal, Vomhof-Dekrey, Emilie E., Tighe, Mike, Koay, Hui-Fern, Godfrey, Dale I., Leadbetter, Elizabeth A., Sant’Angelo, Derek B., von Andrian, Ulrich, Brenner, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4343194/
https://www.ncbi.nlm.nih.gov/pubmed/25436972
http://dx.doi.org/10.1038/ni.3047

Ejemplares similares

Ejemplares similares