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DNA methylation-based subtype prediction for pediatric acute lymphoblastic leukemia

BACKGROUND: We present a method that utilizes DNA methylation profiling for prediction of the cytogenetic subtypes of acute lymphoblastic leukemia (ALL) cells from pediatric ALL patients. The primary aim of our study was to improve risk stratification of ALL patients into treatment groups using DNA...

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Detalles Bibliográficos
Autores principales: Nordlund, Jessica, Bäcklin, Christofer L, Zachariadis, Vasilios, Cavelier, Lucia, Dahlberg, Johan, Öfverholm, Ingegerd, Barbany, Gisela, Nordgren, Ann, Övernäs, Elin, Abrahamsson, Jonas, Flaegstad, Trond, Heyman, Mats M, Jónsson, Ólafur G, Kanerva, Jukka, Larsson, Rolf, Palle, Josefine, Schmiegelow, Kjeld, Gustafsson, Mats G, Lönnerholm, Gudmar, Forestier, Erik, Syvänen, Ann-Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4343276/
https://www.ncbi.nlm.nih.gov/pubmed/25729447
http://dx.doi.org/10.1186/s13148-014-0039-z