Noninvasive Test for Tuberculosis Detection among Primates

Traditional testing methods have limited epidemiologic studies of tuberculosis among free-living primates. PCR amplification of insertion element IS6110 of Mycobacterium tuberculosis from fecal samples was evaluated as a noninvasive screening test for tuberculosis in primates. Active tuberculosis wa...

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Autores principales: Wolf, Tiffany M., Mugisha, Lawrence, Shoyama, Fernanda Miyagaki, O’Malley, Melanie J., Flynn, JoAnne L., Asiimwe, Benon, Travis, Dominic A., Singer, Randall S., Sreevatsan, Srinand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2015
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344255/
https://www.ncbi.nlm.nih.gov/pubmed/25695329
http://dx.doi.org/10.3201/eid2103.140052
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author Wolf, Tiffany M.
Mugisha, Lawrence
Shoyama, Fernanda Miyagaki
O’Malley, Melanie J.
Flynn, JoAnne L.
Asiimwe, Benon
Travis, Dominic A.
Singer, Randall S.
Sreevatsan, Srinand
author_facet Wolf, Tiffany M.
Mugisha, Lawrence
Shoyama, Fernanda Miyagaki
O’Malley, Melanie J.
Flynn, JoAnne L.
Asiimwe, Benon
Travis, Dominic A.
Singer, Randall S.
Sreevatsan, Srinand
author_sort Wolf, Tiffany M.
collection PubMed
description Traditional testing methods have limited epidemiologic studies of tuberculosis among free-living primates. PCR amplification of insertion element IS6110 of Mycobacterium tuberculosis from fecal samples was evaluated as a noninvasive screening test for tuberculosis in primates. Active tuberculosis was detected among inoculated macaques and naturally exposed chimpanzees, demonstrating the utility of this test.
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spelling pubmed-43442552015-03-02 Noninvasive Test for Tuberculosis Detection among Primates Wolf, Tiffany M. Mugisha, Lawrence Shoyama, Fernanda Miyagaki O’Malley, Melanie J. Flynn, JoAnne L. Asiimwe, Benon Travis, Dominic A. Singer, Randall S. Sreevatsan, Srinand Emerg Infect Dis Dispatch Traditional testing methods have limited epidemiologic studies of tuberculosis among free-living primates. PCR amplification of insertion element IS6110 of Mycobacterium tuberculosis from fecal samples was evaluated as a noninvasive screening test for tuberculosis in primates. Active tuberculosis was detected among inoculated macaques and naturally exposed chimpanzees, demonstrating the utility of this test. Centers for Disease Control and Prevention 2015-03 /pmc/articles/PMC4344255/ /pubmed/25695329 http://dx.doi.org/10.3201/eid2103.140052 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Wolf, Tiffany M.
Mugisha, Lawrence
Shoyama, Fernanda Miyagaki
O’Malley, Melanie J.
Flynn, JoAnne L.
Asiimwe, Benon
Travis, Dominic A.
Singer, Randall S.
Sreevatsan, Srinand
Noninvasive Test for Tuberculosis Detection among Primates
title Noninvasive Test for Tuberculosis Detection among Primates
title_full Noninvasive Test for Tuberculosis Detection among Primates
title_fullStr Noninvasive Test for Tuberculosis Detection among Primates
title_full_unstemmed Noninvasive Test for Tuberculosis Detection among Primates
title_short Noninvasive Test for Tuberculosis Detection among Primates
title_sort noninvasive test for tuberculosis detection among primates
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344255/
https://www.ncbi.nlm.nih.gov/pubmed/25695329
http://dx.doi.org/10.3201/eid2103.140052
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