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Mechanism for the Anti-Diabetic Effect of Leptin
Leptin reverses hyperglycemia in T1D though reductions in HPA-mediated lipolysis resulting in reduced hepatic gluconeogenesis through both substrate delivery and allosteric mechanisms.
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344321/ https://www.ncbi.nlm.nih.gov/pubmed/24929951 http://dx.doi.org/10.1038/nm.3579 |
| _version_ | 1782359403504074752 |
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| author | Perry, Rachel J. Zhang, Xian-Man Zhang, Dongyan Kumashiro, Naoki Camporez, Joao-Paulo G. Cline, Gary W. Rothman, Douglas L. Shulman, Gerald I. |
| author_facet | Perry, Rachel J. Zhang, Xian-Man Zhang, Dongyan Kumashiro, Naoki Camporez, Joao-Paulo G. Cline, Gary W. Rothman, Douglas L. Shulman, Gerald I. |
| author_sort | Perry, Rachel J. |
| collection | PubMed |
| description | Leptin reverses hyperglycemia in T1D though reductions in HPA-mediated lipolysis resulting in reduced hepatic gluconeogenesis through both substrate delivery and allosteric mechanisms. |
| format | Online Article Text |
| id | pubmed-4344321 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2014 |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-43443212015-02-27 Mechanism for the Anti-Diabetic Effect of Leptin Perry, Rachel J. Zhang, Xian-Man Zhang, Dongyan Kumashiro, Naoki Camporez, Joao-Paulo G. Cline, Gary W. Rothman, Douglas L. Shulman, Gerald I. Nat Med Article Leptin reverses hyperglycemia in T1D though reductions in HPA-mediated lipolysis resulting in reduced hepatic gluconeogenesis through both substrate delivery and allosteric mechanisms. 2014-06-15 2014-07 /pmc/articles/PMC4344321/ /pubmed/24929951 http://dx.doi.org/10.1038/nm.3579 Text en http://www.nature.com/authors/editorial_policies/license.html#terms Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms |
| spellingShingle | Article Perry, Rachel J. Zhang, Xian-Man Zhang, Dongyan Kumashiro, Naoki Camporez, Joao-Paulo G. Cline, Gary W. Rothman, Douglas L. Shulman, Gerald I. Mechanism for the Anti-Diabetic Effect of Leptin |
| title | Mechanism for the Anti-Diabetic Effect of Leptin |
| title_full | Mechanism for the Anti-Diabetic Effect of Leptin |
| title_fullStr | Mechanism for the Anti-Diabetic Effect of Leptin |
| title_full_unstemmed | Mechanism for the Anti-Diabetic Effect of Leptin |
| title_short | Mechanism for the Anti-Diabetic Effect of Leptin |
| title_sort | mechanism for the anti-diabetic effect of leptin |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344321/ https://www.ncbi.nlm.nih.gov/pubmed/24929951 http://dx.doi.org/10.1038/nm.3579 |
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