Promoter Hypermethylation-Related Reduced Somatostatin Production Promotes Uncontrolled Cell Proliferation in Colorectal Cancer

BACKGROUND: Somatostatin (SST) has anti-proliferative and pro-apoptotic effects. Our aims were to analyze and compare the SST expression during normal aging and colorectal carcinogenesis at mRNA and protein levels. Furthermore, we tested the methylation status of SST in biopsy samples, and the cell...

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Detalles Bibliográficos
Autores principales: Leiszter, Katalin, Sipos, Ferenc, Galamb, Orsolya, Krenács, Tibor, Veres, Gábor, Wichmann, Barna, Fűri, István, Kalmár, Alexandra, Patai, Árpád V., Tóth, Kinga, Valcz, Gábor, Tulassay, Zsolt, Molnár, Béla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344335/
https://www.ncbi.nlm.nih.gov/pubmed/25723531
http://dx.doi.org/10.1371/journal.pone.0118332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344335/
https://www.ncbi.nlm.nih.gov/pubmed/25723531
http://dx.doi.org/10.1371/journal.pone.0118332

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