Identification of Effective Subdominant Anti-HIV-1 CD8+ T Cells Within Entire Post-infection and Post-vaccination Immune Responses

Defining the components of an HIV immunogen that could induce effective CD8+ T cell responses is critical to vaccine development. We addressed this question by investigating the viral targets of CD8+ T cells that potently inhibit HIV replication in vitro, as this is highly predictive of virus contro...

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Detalles Bibliográficos
Autores principales: Hancock, Gemma, Yang, Hongbing, Yorke, Elisabeth, Wainwright, Emma, Bourne, Victoria, Frisbee, Alyse, Payne, Tamika L., Berrong, Mark, Ferrari, Guido, Chopera, Denis, Hanke, Tomas, Mothe, Beatriz, Brander, Christian, McElrath, M. Juliana, McMichael, Andrew, Goonetilleke, Nilu, Tomaras, Georgia D., Frahm, Nicole, Dorrell, Lucy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344337/
https://www.ncbi.nlm.nih.gov/pubmed/25723536
http://dx.doi.org/10.1371/journal.ppat.1004658

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