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STAMP: Sequence tag-based analysis of microbial population dynamics
We describe a new method (STAMP) for characterization of pathogen population dynamics during infection. STAMP analyzes the frequency changes of genetically “barcoded” organisms to quantify population bottlenecks and infer the founding population size. Analyses of intra-intestinal Vibrio cholerae rev...
Autores principales: | Abel, Sören, zur Wiesch, Pia Abel, Chang, Hsiao-Han, Davis, Brigid M., Lipsitch, Marc, Waldor, Matthew K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344388/ https://www.ncbi.nlm.nih.gov/pubmed/25599549 http://dx.doi.org/10.1038/nmeth.3253 |
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