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Signal Transduction by a Fungal NOD-Like Receptor Based on Propagation of a Prion Amyloid Fold
In the fungus Podospora anserina, the [Het-s] prion induces programmed cell death by activating the HET-S pore-forming protein. The HET-s β-solenoid prion fold serves as a template for converting the HET-S prion-forming domain into the same fold. This conversion, in turn, activates the HET-S pore-fo...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344463/ https://www.ncbi.nlm.nih.gov/pubmed/25671553 http://dx.doi.org/10.1371/journal.pbio.1002059 |