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Conformational changes in the P site and mRNA entry channel evoked by AUG recognition in yeast translation preinitiation complexes

The translation preinitiation complex (PIC) is thought to assume an open conformation when scanning the mRNA leader, with AUG recognition evoking a closed conformation and more stable P site interaction of Met-tRNA(i); however, physical evidence is lacking that AUG recognition constrains interaction...

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Detalles Bibliográficos
Autores principales:	Zhang, Fan, Saini, Adesh K., Shin, Byung-Sik, Nanda, Jagpreet, Hinnebusch, Alan G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344491/ https://www.ncbi.nlm.nih.gov/pubmed/25670678 http://dx.doi.org/10.1093/nar/gkv028

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