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Insights into the mechanism of a G-quadruplex-unwinding DEAH-box helicase

The unwinding of nucleic acid secondary structures within cells is crucial to maintain genomic integrity and prevent abortive transcription and translation initiation. DHX36, also known as RHAU or G4R1, is a DEAH-box ATP-dependent helicase highly specific for DNA and RNA G-quadruplexes (G4s). A fund...

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Detalles Bibliográficos
Autores principales:	Chen, Michael C., Murat, Pierre, Abecassis, Keren, Ferré-D'Amaré, Adrian R., Balasubramanian, Shankar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344499/ https://www.ncbi.nlm.nih.gov/pubmed/25653156 http://dx.doi.org/10.1093/nar/gkv051

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