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Impact of template backbone heterogeneity on RNA polymerase II transcription

Variations in the sugar component (ribose or deoxyribose) and the nature of the phosphodiester linkage (3′-5′ or 2′-5′ orientation) have been a challenge for genetic information transfer from the very beginning of evolution. RNA polymerase II (pol II) governs the transcription of DNA into precursor...

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Detalles Bibliográficos
Autores principales: Xu, Liang, Wang, Wei, Zhang, Lu, Chong, Jenny, Huang, Xuhui, Wang, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344504/
https://www.ncbi.nlm.nih.gov/pubmed/25662224
http://dx.doi.org/10.1093/nar/gkv059