Structural and functional characterization of a cell cycle associated HDAC1/2 complex reveals the structural basis for complex assembly and nucleosome targeting

Recent proteomic studies have identified a novel histone deacetylase complex that is upregulated during mitosis and is associated with cyclin A. This complex is conserved from nematodes to man and contains histone deacetylases 1 and 2, the MIDEAS corepressor protein and a protein called DNTTIP1 whos...

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Detalles Bibliográficos
Autores principales: Itoh, Toshimasa, Fairall, Louise, Muskett, Frederick W., Milano, Charles P., Watson, Peter J., Arnaudo, Nadia, Saleh, Almutasem, Millard, Christopher J., El-Mezgueldi, Mohammed, Martino, Fabrizio, Schwabe, John W.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344507/
https://www.ncbi.nlm.nih.gov/pubmed/25653165
http://dx.doi.org/10.1093/nar/gkv068

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