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FF(483–484) motif of human Polη mediates its interaction with the POLD2 subunit of Polδ and contributes to DNA damage tolerance

Switching between replicative and translesion synthesis (TLS) DNA polymerases are crucial events for the completion of genomic DNA synthesis when the replication machinery encounters lesions in the DNA template. In eukaryotes, the translesional DNA polymerase η (Polη) plays a central role for accura...

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Detalles Bibliográficos
Autores principales: Baldeck, Nadège, Janel-Bintz, Régine, Wagner, Jérome, Tissier, Agnès, Fuchs, Robert P., Burkovics, Peter, Haracska, Lajos, Despras, Emmanuelle, Bichara, Marc, Chatton, Bruno, Cordonnier, Agnès M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344513/
https://www.ncbi.nlm.nih.gov/pubmed/25662213
http://dx.doi.org/10.1093/nar/gkv076