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FF(483–484) motif of human Polη mediates its interaction with the POLD2 subunit of Polδ and contributes to DNA damage tolerance
Switching between replicative and translesion synthesis (TLS) DNA polymerases are crucial events for the completion of genomic DNA synthesis when the replication machinery encounters lesions in the DNA template. In eukaryotes, the translesional DNA polymerase η (Polη) plays a central role for accura...
Autores principales: | Baldeck, Nadège, Janel-Bintz, Régine, Wagner, Jérome, Tissier, Agnès, Fuchs, Robert P., Burkovics, Peter, Haracska, Lajos, Despras, Emmanuelle, Bichara, Marc, Chatton, Bruno, Cordonnier, Agnès M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344513/ https://www.ncbi.nlm.nih.gov/pubmed/25662213 http://dx.doi.org/10.1093/nar/gkv076 |
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