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Direct observation of the translocation mechanism of transcription termination factor Rho
Rho is a ring-shaped, ATP-fueled motor essential for remodeling transcriptional complexes and R-loops in bacteria. Despite years of research on this fundamental model helicase, key aspects of its mechanism of translocation remain largely unknown. Here, we used single-molecule manipulation and fluore...
Autores principales: | Gocheva, Veronika, Le Gall, Antoine, Boudvillain, Marc, Margeat, Emmanuel, Nollmann, Marcelo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344519/ https://www.ncbi.nlm.nih.gov/pubmed/25662222 http://dx.doi.org/10.1093/nar/gkv085 |
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