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Direct observation of the translocation mechanism of transcription termination factor Rho

Rho is a ring-shaped, ATP-fueled motor essential for remodeling transcriptional complexes and R-loops in bacteria. Despite years of research on this fundamental model helicase, key aspects of its mechanism of translocation remain largely unknown. Here, we used single-molecule manipulation and fluore...

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Detalles Bibliográficos
Autores principales: Gocheva, Veronika, Le Gall, Antoine, Boudvillain, Marc, Margeat, Emmanuel, Nollmann, Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344519/
https://www.ncbi.nlm.nih.gov/pubmed/25662222
http://dx.doi.org/10.1093/nar/gkv085

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