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FUBP1: a new protagonist in splicing regulation of the DMD gene

We investigated the molecular mechanisms for in-frame skipping of DMD exon 39 caused by the nonsense c.5480T>A mutation in a patient with Becker muscular dystrophy. RNase-assisted pull down assay coupled with mass spectrometry revealed that the mutant RNA probe specifically recruits hnRNPA1, hnRN...

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Detalles Bibliográficos
Autores principales:	Miro, Julie, Laaref, Abdelhamid Mahdi, Rofidal, Valérie, Lagrafeuille, Rosyne, Hem, Sonia, Thorel, Delphine, Méchin, Déborah, Mamchaoui, Kamel, Mouly, Vincent, Claustres, Mireille, Tuffery-Giraud, Sylvie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344520/ https://www.ncbi.nlm.nih.gov/pubmed/25662218 http://dx.doi.org/10.1093/nar/gkv086

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