Cargando…
The regulation and deregulation of Wnt signaling by PARK genes in health and disease
Wingless/Int (Wnt) signaling pathways are signal transduction mechanisms that have been widely studied in the field of embryogenesis. Recent work has established a critical role for these pathways in brain development, especially of midbrain dopaminergic neurones. However, the fundamental importance...
Autores principales: | Berwick, Daniel C., Harvey, Kirsten |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344548/ https://www.ncbi.nlm.nih.gov/pubmed/24115276 http://dx.doi.org/10.1093/jmcb/mjt037 |
Ejemplares similares
-
LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6
por: Berwick, Daniel C., et al.
Publicado: (2012) -
LRRK2: an éminence grise of Wnt-mediated neurogenesis?
por: Berwick, Daniel C., et al.
Publicado: (2013) -
Wnt Signaling Deregulation in the Aging and Alzheimer’s Brain
por: Palomer, Ernest, et al.
Publicado: (2019) -
Environmental Exposure to Heavy Metals Contributes to Diseases Via Deregulated Wnt Signaling Pathways
por: Khalid, Madiha, et al.
Publicado: (2021) -
Protective LRRK2 R1398H Variant Enhances GTPase and Wnt Signaling Activity
por: Nixon-Abell, Jonathon, et al.
Publicado: (2016)