Cargando…
Black Tea Lowers Blood Pressure and Wave Reflections in Fasted and Postprandial Conditions in Hypertensive Patients: A Randomised Study
Hypertension and arterial stiffening are independent predictors of cardiovascular mortality. Flavonoids may exert some vascular protection. We investigated the effects of black tea on blood pressure (BP) and wave reflections before and after fat load in hypertensives. According to a randomized, doub...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344573/ https://www.ncbi.nlm.nih.gov/pubmed/25658240 http://dx.doi.org/10.3390/nu7021037 |
_version_ | 1782359440339501056 |
---|---|
author | Grassi, Davide Draijer, Richard Desideri, Giovambattista Mulder, Theo Ferri, Claudio |
author_facet | Grassi, Davide Draijer, Richard Desideri, Giovambattista Mulder, Theo Ferri, Claudio |
author_sort | Grassi, Davide |
collection | PubMed |
description | Hypertension and arterial stiffening are independent predictors of cardiovascular mortality. Flavonoids may exert some vascular protection. We investigated the effects of black tea on blood pressure (BP) and wave reflections before and after fat load in hypertensives. According to a randomized, double-blind, controlled, cross-over design, 19 patients were assigned to consume black tea (129 mg flavonoids) or placebo twice a day for eight days (13 day wash-out period). Digital volume pulse and BP were measured before and 1, 2, 3 and 4 h after tea consumption. Measurements were performed in a fasted state and after a fat load. Compared to placebo, reflection index and stiffness index decreased after tea consumption (p < 0.0001). Fat challenge increased wave reflection, which was counteracted by tea consumption (p < 0.0001). Black tea decreased systolic and diastolic BP (−3.2 mmHg, p < 0.005 and −2.6 mmHg, p < 0.0001; respectively) and prevented BP increase after a fat load (p < 0.0001). Black tea consumption lowers wave reflections and BP in the fasting state, and during the challenging haemodynamic conditions after a fat load in hypertensives. Considering lipemia-induced impairment of arterial function may occur frequently during the day, our findings suggest regular consumption of black tea may be relevant for cardiovascular protection. |
format | Online Article Text |
id | pubmed-4344573 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-43445732015-03-18 Black Tea Lowers Blood Pressure and Wave Reflections in Fasted and Postprandial Conditions in Hypertensive Patients: A Randomised Study Grassi, Davide Draijer, Richard Desideri, Giovambattista Mulder, Theo Ferri, Claudio Nutrients Article Hypertension and arterial stiffening are independent predictors of cardiovascular mortality. Flavonoids may exert some vascular protection. We investigated the effects of black tea on blood pressure (BP) and wave reflections before and after fat load in hypertensives. According to a randomized, double-blind, controlled, cross-over design, 19 patients were assigned to consume black tea (129 mg flavonoids) or placebo twice a day for eight days (13 day wash-out period). Digital volume pulse and BP were measured before and 1, 2, 3 and 4 h after tea consumption. Measurements were performed in a fasted state and after a fat load. Compared to placebo, reflection index and stiffness index decreased after tea consumption (p < 0.0001). Fat challenge increased wave reflection, which was counteracted by tea consumption (p < 0.0001). Black tea decreased systolic and diastolic BP (−3.2 mmHg, p < 0.005 and −2.6 mmHg, p < 0.0001; respectively) and prevented BP increase after a fat load (p < 0.0001). Black tea consumption lowers wave reflections and BP in the fasting state, and during the challenging haemodynamic conditions after a fat load in hypertensives. Considering lipemia-induced impairment of arterial function may occur frequently during the day, our findings suggest regular consumption of black tea may be relevant for cardiovascular protection. MDPI 2015-02-04 /pmc/articles/PMC4344573/ /pubmed/25658240 http://dx.doi.org/10.3390/nu7021037 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Grassi, Davide Draijer, Richard Desideri, Giovambattista Mulder, Theo Ferri, Claudio Black Tea Lowers Blood Pressure and Wave Reflections in Fasted and Postprandial Conditions in Hypertensive Patients: A Randomised Study |
title | Black Tea Lowers Blood Pressure and Wave Reflections in Fasted and Postprandial Conditions in Hypertensive Patients: A Randomised Study |
title_full | Black Tea Lowers Blood Pressure and Wave Reflections in Fasted and Postprandial Conditions in Hypertensive Patients: A Randomised Study |
title_fullStr | Black Tea Lowers Blood Pressure and Wave Reflections in Fasted and Postprandial Conditions in Hypertensive Patients: A Randomised Study |
title_full_unstemmed | Black Tea Lowers Blood Pressure and Wave Reflections in Fasted and Postprandial Conditions in Hypertensive Patients: A Randomised Study |
title_short | Black Tea Lowers Blood Pressure and Wave Reflections in Fasted and Postprandial Conditions in Hypertensive Patients: A Randomised Study |
title_sort | black tea lowers blood pressure and wave reflections in fasted and postprandial conditions in hypertensive patients: a randomised study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344573/ https://www.ncbi.nlm.nih.gov/pubmed/25658240 http://dx.doi.org/10.3390/nu7021037 |
work_keys_str_mv | AT grassidavide blacktealowersbloodpressureandwavereflectionsinfastedandpostprandialconditionsinhypertensivepatientsarandomisedstudy AT draijerrichard blacktealowersbloodpressureandwavereflectionsinfastedandpostprandialconditionsinhypertensivepatientsarandomisedstudy AT desiderigiovambattista blacktealowersbloodpressureandwavereflectionsinfastedandpostprandialconditionsinhypertensivepatientsarandomisedstudy AT muldertheo blacktealowersbloodpressureandwavereflectionsinfastedandpostprandialconditionsinhypertensivepatientsarandomisedstudy AT ferriclaudio blacktealowersbloodpressureandwavereflectionsinfastedandpostprandialconditionsinhypertensivepatientsarandomisedstudy |