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Uptake of Clostridium botulinum C3 Exoenzyme into Intact HT22 and J774A.1 Cells

The Clostridium botulinum C3 exoenzyme selectively ADP-ribosylates low molecular weight GTP-binding proteins RhoA, B and C. This covalent modification inhibits Rho signaling activity, resulting in distinct actin cytoskeleton changes. Although C3 exoenzyme has no binding, the translocation domain ass...

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Detalles Bibliográficos
Autores principales:	Rohrbeck, Astrid, von Elsner, Leonie, Hagemann, Sandra, Just, Ingo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344630/ https://www.ncbi.nlm.nih.gov/pubmed/25648844 http://dx.doi.org/10.3390/toxins7020380

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