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Induced pluripotent stem cell-derived neuronal cells from a sporadic Alzheimer’s disease donor as a model for investigating AD-associated gene regulatory networks

BACKGROUND: Alzheimer’s disease (AD) is a complex, irreversible neurodegenerative disorder. At present there are neither reliable markers to diagnose AD at an early stage nor therapy. To investigate underlying disease mechanisms, induced pluripotent stem cells (iPSCs) allow the generation of patient...

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Detalles Bibliográficos
Autores principales:	Hossini, Amir M, Megges, Matthias, Prigione, Alessandro, Lichtner, Bjoern, Toliat, Mohammad R, Wruck, Wasco, Schröter, Friederike, Nuernberg, Peter, Kroll, Hartmut, Makrantonaki, Eugenia, Zoubouliss, Christos C, Adjaye, James
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344782/ https://www.ncbi.nlm.nih.gov/pubmed/25765079 http://dx.doi.org/10.1186/s12864-015-1262-5

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