A reassessment of soluble urokinase-type plasminogen activator receptor in glomerular disease

It has been suggested that soluble urokinase receptor (suPAR) is a causative circulating factor for and a biomarker of focal and segmental glomerulosclerosis (FSGS). Here we undertook validation of these assumptions in both mouse and human models. Injection of recombinant suPAR in wild-type mice did...

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Detalles Bibliográficos
Autores principales: Spinale, Joann M., Mariani, Laura H., Kapoor, Shiv, Zhang, Jidong, Weyant, Robert, Song, Peter X., Wong, Hetty N., Troost, Jonathan P., Gadegbeku, Crystal A., Gipson, Debbie S., Kretzler, Matthias, Nihalani, Deepak, Holzman, Lawrence B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344842/
https://www.ncbi.nlm.nih.gov/pubmed/25354239
http://dx.doi.org/10.1038/ki.2014.346

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