Hypo Adenosine-to-Inosine miR-455-5p Editing Promotes Melanoma Growth and Metastasis

Although recent studies have shown that adenosine-to-inosine (A-to-I) RNA editing occurs in microRNAs, its effects on tumor growth and metastasis are not well understood. We present evidence of CREB-mediated low expression of ADAR1 in metastatic melanoma cell lines and tumor specimens. Re-expression...

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Detalles Bibliográficos
Autores principales: Shoshan, Einav, Mobley, Aaron K., Braeuer, Russell R., Kamiya, Takafumi, Huang, Li, Vasquez, Mayra E., Salameh, Ahmad, Lee, Ho Jeong, Kim, Sun Jin, Ivan, Cristina, Velazquez-Torres, Guermarie, Nip, Ka Ming, Zhu, Kelsey, Brooks, Denise, Jones, Steven J.M., Birol, Inanc, Mosqueda, Maribel, Wen, Yu-ye, Eterovic, Agda Karina, Sood, Anil K., Hwu, Patrick, Gershenwald, Jeffrey E, Robertson, A. Gordon, Calin, George A., Markel, Gal, Fidler, Isaiah J., Bar-Eli, Menashe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344852/
https://www.ncbi.nlm.nih.gov/pubmed/25686251
http://dx.doi.org/10.1038/ncb3110

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