Cargando…
Huntingtin Functions as a Scaffold for Selective Macroautophagy
Selective macroautophagy is an important protective mechanism against diverse cellular stresses. In contrast to the well-characterized starvation-induced autophagy, the regulation of selective autophagy is largely unknown. Here, we demonstrate that Huntingtin, the Huntington’s disease gene product,...
Autores principales: | Rui, Yan-Ning, Xu, Zhen, Patel, Bindi, Chen, Zhihua, Chen, Dongsheng, Tito, Antonio, David, Gabriela, Sun, Yamin, Stimming, Erin F., Bellen, Hugo, Cuervo, Ana Maria, Zhang, Sheng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344873/ https://www.ncbi.nlm.nih.gov/pubmed/25686248 http://dx.doi.org/10.1038/ncb3101 |
Ejemplares similares
-
HAP40 is a conserved central regulator of Huntingtin and a potential modulator of Huntington’s disease pathogenesis
por: Xu, Shiyu, et al.
Publicado: (2022) -
Aggrephagy: Selective Disposal of Protein Aggregates by Macroautophagy
por: Lamark, Trond, et al.
Publicado: (2012) -
Macroautophagy Abnormality in Essential Tremor
por: Kuo, Sheng-Han, et al.
Publicado: (2012) -
Analysis of macroautophagy by immunohistochemistry
por: Rosenfeldt, Mathias T., et al.
Publicado: (2012) -
Macroautophagy in T Lymphocyte Development and Function
por: He, Ming-Xiao, et al.
Publicado: (2012)