Genome-wide epistatic expression quantitative trait loci discovery in four human tissues reveals the importance of local chromosomal interactions governing gene expression

BACKGROUND: Epistasis (synergistic interaction) among SNPs governing gene expression is likely to arise within transcriptional networks. However, the power to detect it is limited by the large number of combinations to be tested and the modest sample sizes of most datasets. By limiting the interacti...

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Detalles Bibliográficos
Autores principales: Fitzpatrick, Darren J, Ryan, Colm J, Shah, Naisha, Greene, Derek, Molony, Cliona, Shields, Denis C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345003/
https://www.ncbi.nlm.nih.gov/pubmed/25765234
http://dx.doi.org/10.1186/s12864-015-1300-3

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