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Autophagy regulates tissue overgrowth in a context-dependent manner

Autophagy is a catabolic process that has been implicated as both a tumor suppressor and in tumor progression. Here, we investigate this dichotomy in cancer biology by studying the influence of altered autophagy in Drosophila models of tissue overgrowth. We find that the impact of altered autophagy...

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Detalles Bibliográficos
Autores principales: Pérez, Ernesto, Das, Gautam, Bergmann, Andreas, Baehrecke, Eric H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345156/
https://www.ncbi.nlm.nih.gov/pubmed/25174403
http://dx.doi.org/10.1038/onc.2014.285