Appearance and Disappearance of Chronic Myeloid Leukemia (CML) in Patient with Chronic Lymphocytic Leukemia (CLL)

Chronic lymphocytic leukemia (CLL) and chronic myeloid leukemia (CML) are the most common leukemias of the elderly (>43 year). However, the sequential occurrence of CML followed by CLL in the same patient is extremely rare. In our report, a 52-year-old female was diagnosed with CLL (type of bone...

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Autores principales: Payandeh, Mehrdad, Sadeghi, Edris, Khodarahmi, Reza, Sadeghi, Masoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345298/
https://www.ncbi.nlm.nih.gov/pubmed/25774268
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author Payandeh, Mehrdad
Sadeghi, Edris
Khodarahmi, Reza
Sadeghi, Masoud
author_facet Payandeh, Mehrdad
Sadeghi, Edris
Khodarahmi, Reza
Sadeghi, Masoud
author_sort Payandeh, Mehrdad
collection PubMed
description Chronic lymphocytic leukemia (CLL) and chronic myeloid leukemia (CML) are the most common leukemias of the elderly (>43 year). However, the sequential occurrence of CML followed by CLL in the same patient is extremely rare. In our report, a 52-year-old female was diagnosed with CLL (type of bone marrow (BM) infiltration was nodular and interstitial) and was treated with chlorambucil. 64 months after the diagnosis of CLL, she developed CML. She was treated with imatinib (400mg/day). After a few months, signs of CML were disappeared and CLL became dominant. This is first reported case.
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spelling pubmed-43452982015-03-13 Appearance and Disappearance of Chronic Myeloid Leukemia (CML) in Patient with Chronic Lymphocytic Leukemia (CLL) Payandeh, Mehrdad Sadeghi, Edris Khodarahmi, Reza Sadeghi, Masoud Int J Hematol Oncol Stem Cell Res Case Report Chronic lymphocytic leukemia (CLL) and chronic myeloid leukemia (CML) are the most common leukemias of the elderly (>43 year). However, the sequential occurrence of CML followed by CLL in the same patient is extremely rare. In our report, a 52-year-old female was diagnosed with CLL (type of bone marrow (BM) infiltration was nodular and interstitial) and was treated with chlorambucil. 64 months after the diagnosis of CLL, she developed CML. She was treated with imatinib (400mg/day). After a few months, signs of CML were disappeared and CLL became dominant. This is first reported case. Tehran University of Medical Sciences 2014-10-01 /pmc/articles/PMC4345298/ /pubmed/25774268 Text en Copyright: © International Journal of Hematology-Oncology and Stem Cell Research & Tehran University of Medical Sciences This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
spellingShingle Case Report
Payandeh, Mehrdad
Sadeghi, Edris
Khodarahmi, Reza
Sadeghi, Masoud
Appearance and Disappearance of Chronic Myeloid Leukemia (CML) in Patient with Chronic Lymphocytic Leukemia (CLL)
title Appearance and Disappearance of Chronic Myeloid Leukemia (CML) in Patient with Chronic Lymphocytic Leukemia (CLL)
title_full Appearance and Disappearance of Chronic Myeloid Leukemia (CML) in Patient with Chronic Lymphocytic Leukemia (CLL)
title_fullStr Appearance and Disappearance of Chronic Myeloid Leukemia (CML) in Patient with Chronic Lymphocytic Leukemia (CLL)
title_full_unstemmed Appearance and Disappearance of Chronic Myeloid Leukemia (CML) in Patient with Chronic Lymphocytic Leukemia (CLL)
title_short Appearance and Disappearance of Chronic Myeloid Leukemia (CML) in Patient with Chronic Lymphocytic Leukemia (CLL)
title_sort appearance and disappearance of chronic myeloid leukemia (cml) in patient with chronic lymphocytic leukemia (cll)
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345298/
https://www.ncbi.nlm.nih.gov/pubmed/25774268
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