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Acceleration of genetic gain in cattle by reduction of generation interval

Genomic selection (GS) approaches, in combination with reproductive technologies, are revolutionizing the design and implementation of breeding programs in livestock species, particularly in cattle. GS leverages genomic readouts to provide estimates of breeding value early in the life of animals. Ho...

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Autores principales: Kasinathan, Poothappillai, Wei, Hong, Xiang, Tianhao, Molina, Jose A., Metzger, John, Broek, Diane, Kasinathan, Sivakanthan, Faber, David C., Allan, Mark F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345332/
https://www.ncbi.nlm.nih.gov/pubmed/25728468
http://dx.doi.org/10.1038/srep08674
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author Kasinathan, Poothappillai
Wei, Hong
Xiang, Tianhao
Molina, Jose A.
Metzger, John
Broek, Diane
Kasinathan, Sivakanthan
Faber, David C.
Allan, Mark F.
author_facet Kasinathan, Poothappillai
Wei, Hong
Xiang, Tianhao
Molina, Jose A.
Metzger, John
Broek, Diane
Kasinathan, Sivakanthan
Faber, David C.
Allan, Mark F.
author_sort Kasinathan, Poothappillai
collection PubMed
description Genomic selection (GS) approaches, in combination with reproductive technologies, are revolutionizing the design and implementation of breeding programs in livestock species, particularly in cattle. GS leverages genomic readouts to provide estimates of breeding value early in the life of animals. However, the capacity of these approaches for improving genetic gain in breeding programs is limited by generation interval, the average age of an animal when replacement progeny are born. Here, we present a cost-effective approach that combines GS with reproductive technologies to reduce generation interval by rapidly producing high genetic merit calves.
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spelling pubmed-43453322015-03-10 Acceleration of genetic gain in cattle by reduction of generation interval Kasinathan, Poothappillai Wei, Hong Xiang, Tianhao Molina, Jose A. Metzger, John Broek, Diane Kasinathan, Sivakanthan Faber, David C. Allan, Mark F. Sci Rep Article Genomic selection (GS) approaches, in combination with reproductive technologies, are revolutionizing the design and implementation of breeding programs in livestock species, particularly in cattle. GS leverages genomic readouts to provide estimates of breeding value early in the life of animals. However, the capacity of these approaches for improving genetic gain in breeding programs is limited by generation interval, the average age of an animal when replacement progeny are born. Here, we present a cost-effective approach that combines GS with reproductive technologies to reduce generation interval by rapidly producing high genetic merit calves. Nature Publishing Group 2015-03-02 /pmc/articles/PMC4345332/ /pubmed/25728468 http://dx.doi.org/10.1038/srep08674 Text en Copyright © 2015, Macmillan Publishers Limited. All rights reserved http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder in order to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Kasinathan, Poothappillai
Wei, Hong
Xiang, Tianhao
Molina, Jose A.
Metzger, John
Broek, Diane
Kasinathan, Sivakanthan
Faber, David C.
Allan, Mark F.
Acceleration of genetic gain in cattle by reduction of generation interval
title Acceleration of genetic gain in cattle by reduction of generation interval
title_full Acceleration of genetic gain in cattle by reduction of generation interval
title_fullStr Acceleration of genetic gain in cattle by reduction of generation interval
title_full_unstemmed Acceleration of genetic gain in cattle by reduction of generation interval
title_short Acceleration of genetic gain in cattle by reduction of generation interval
title_sort acceleration of genetic gain in cattle by reduction of generation interval
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345332/
https://www.ncbi.nlm.nih.gov/pubmed/25728468
http://dx.doi.org/10.1038/srep08674
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