The Synergistic Effect of Bleomycin, Triamcinolone and Epinephrine in Treatment of Hemangioma and Arteriovenous Malformations

BACKGROUND: Hemangioma is the most common tumor of neonatal period and it is almost always appeared by the end of the first week of life and can be found mostly in head and neck area. This study evaluated the synergistic effect of bleomycin, triamcinolone and epinephrine in treatment of hemangioma a...

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Detalles Bibliográficos
Autores principales: Masiha, Hamid, Nikpour, Heydar Ali, Hasani, Mohammad Esmaeil, Emami, Abolhasan, Jafari, Mehryar, Manafi, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Society for Plastic Surgeons 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345433/
https://www.ncbi.nlm.nih.gov/pubmed/25734049
Descripción
Sumario:BACKGROUND: Hemangioma is the most common tumor of neonatal period and it is almost always appeared by the end of the first week of life and can be found mostly in head and neck area. This study evaluated the synergistic effect of bleomycin, triamcinolone and epinephrine in treatment of hemangioma and arteriovenous malformations. METHODS: In this multicenter study, a combination of bleomycin, triamcinolone and epinephrine was injected intralesionaly for treatment of hemangiomas and arteriovenous malformations and their synergistic effect was evaluated in 32 patients. RESULTS: Hemangiomas and low-flow arteriovenous malformations were treated well with their combination while port-wine spots and high-flow lesions response were relatively poor. CONCLUSION: It seems that the combination of bleomycin, triamcinolone and epinephrine may be a good choice in treatment of hemangioma and arteriovenous malformations.

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