The Synergistic Effect of Bleomycin, Triamcinolone and Epinephrine in Treatment of Hemangioma and Arteriovenous Malformations

BACKGROUND: Hemangioma is the most common tumor of neonatal period and it is almost always appeared by the end of the first week of life and can be found mostly in head and neck area. This study evaluated the synergistic effect of bleomycin, triamcinolone and epinephrine in treatment of hemangioma a...

Descripción completa

Detalles Bibliográficos
Autores principales: Masiha, Hamid, Nikpour, Heydar Ali, Hasani, Mohammad Esmaeil, Emami, Abolhasan, Jafari, Mehryar, Manafi, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Society for Plastic Surgeons 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345433/
https://www.ncbi.nlm.nih.gov/pubmed/25734049
_version_ 1782359579775991808
author Masiha, Hamid
Nikpour, Heydar Ali
Hasani, Mohammad Esmaeil
Emami, Abolhasan
Jafari, Mehryar
Manafi, Ali
author_facet Masiha, Hamid
Nikpour, Heydar Ali
Hasani, Mohammad Esmaeil
Emami, Abolhasan
Jafari, Mehryar
Manafi, Ali
author_sort Masiha, Hamid
collection PubMed
description BACKGROUND: Hemangioma is the most common tumor of neonatal period and it is almost always appeared by the end of the first week of life and can be found mostly in head and neck area. This study evaluated the synergistic effect of bleomycin, triamcinolone and epinephrine in treatment of hemangioma and arteriovenous malformations. METHODS: In this multicenter study, a combination of bleomycin, triamcinolone and epinephrine was injected intralesionaly for treatment of hemangiomas and arteriovenous malformations and their synergistic effect was evaluated in 32 patients. RESULTS: Hemangiomas and low-flow arteriovenous malformations were treated well with their combination while port-wine spots and high-flow lesions response were relatively poor. CONCLUSION: It seems that the combination of bleomycin, triamcinolone and epinephrine may be a good choice in treatment of hemangioma and arteriovenous malformations.
format Online
Article
Text
id pubmed-4345433
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Iranian Society for Plastic Surgeons
record_format MEDLINE/PubMed
spelling pubmed-43454332015-03-02 The Synergistic Effect of Bleomycin, Triamcinolone and Epinephrine in Treatment of Hemangioma and Arteriovenous Malformations Masiha, Hamid Nikpour, Heydar Ali Hasani, Mohammad Esmaeil Emami, Abolhasan Jafari, Mehryar Manafi, Ali World J Plast Surg Original Article BACKGROUND: Hemangioma is the most common tumor of neonatal period and it is almost always appeared by the end of the first week of life and can be found mostly in head and neck area. This study evaluated the synergistic effect of bleomycin, triamcinolone and epinephrine in treatment of hemangioma and arteriovenous malformations. METHODS: In this multicenter study, a combination of bleomycin, triamcinolone and epinephrine was injected intralesionaly for treatment of hemangiomas and arteriovenous malformations and their synergistic effect was evaluated in 32 patients. RESULTS: Hemangiomas and low-flow arteriovenous malformations were treated well with their combination while port-wine spots and high-flow lesions response were relatively poor. CONCLUSION: It seems that the combination of bleomycin, triamcinolone and epinephrine may be a good choice in treatment of hemangioma and arteriovenous malformations. Iranian Society for Plastic Surgeons 2012-07 /pmc/articles/PMC4345433/ /pubmed/25734049 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Masiha, Hamid
Nikpour, Heydar Ali
Hasani, Mohammad Esmaeil
Emami, Abolhasan
Jafari, Mehryar
Manafi, Ali
The Synergistic Effect of Bleomycin, Triamcinolone and Epinephrine in Treatment of Hemangioma and Arteriovenous Malformations
title The Synergistic Effect of Bleomycin, Triamcinolone and Epinephrine in Treatment of Hemangioma and Arteriovenous Malformations
title_full The Synergistic Effect of Bleomycin, Triamcinolone and Epinephrine in Treatment of Hemangioma and Arteriovenous Malformations
title_fullStr The Synergistic Effect of Bleomycin, Triamcinolone and Epinephrine in Treatment of Hemangioma and Arteriovenous Malformations
title_full_unstemmed The Synergistic Effect of Bleomycin, Triamcinolone and Epinephrine in Treatment of Hemangioma and Arteriovenous Malformations
title_short The Synergistic Effect of Bleomycin, Triamcinolone and Epinephrine in Treatment of Hemangioma and Arteriovenous Malformations
title_sort synergistic effect of bleomycin, triamcinolone and epinephrine in treatment of hemangioma and arteriovenous malformations
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345433/
https://www.ncbi.nlm.nih.gov/pubmed/25734049
work_keys_str_mv AT masihahamid thesynergisticeffectofbleomycintriamcinoloneandepinephrineintreatmentofhemangiomaandarteriovenousmalformations
AT nikpourheydarali thesynergisticeffectofbleomycintriamcinoloneandepinephrineintreatmentofhemangiomaandarteriovenousmalformations
AT hasanimohammadesmaeil thesynergisticeffectofbleomycintriamcinoloneandepinephrineintreatmentofhemangiomaandarteriovenousmalformations
AT emamiabolhasan thesynergisticeffectofbleomycintriamcinoloneandepinephrineintreatmentofhemangiomaandarteriovenousmalformations
AT jafarimehryar thesynergisticeffectofbleomycintriamcinoloneandepinephrineintreatmentofhemangiomaandarteriovenousmalformations
AT manafiali thesynergisticeffectofbleomycintriamcinoloneandepinephrineintreatmentofhemangiomaandarteriovenousmalformations
AT masihahamid synergisticeffectofbleomycintriamcinoloneandepinephrineintreatmentofhemangiomaandarteriovenousmalformations
AT nikpourheydarali synergisticeffectofbleomycintriamcinoloneandepinephrineintreatmentofhemangiomaandarteriovenousmalformations
AT hasanimohammadesmaeil synergisticeffectofbleomycintriamcinoloneandepinephrineintreatmentofhemangiomaandarteriovenousmalformations
AT emamiabolhasan synergisticeffectofbleomycintriamcinoloneandepinephrineintreatmentofhemangiomaandarteriovenousmalformations
AT jafarimehryar synergisticeffectofbleomycintriamcinoloneandepinephrineintreatmentofhemangiomaandarteriovenousmalformations
AT manafiali synergisticeffectofbleomycintriamcinoloneandepinephrineintreatmentofhemangiomaandarteriovenousmalformations

Ejemplares similares