Role of Wnt signaling in fracture healing

The Wnt signaling pathway is well known to play major roles in skeletal development and homeostasis. In certain aspects, fracture repair mimics the process of bone embryonic development. Thus, the importance of Wnt signaling in fracture healing has become more apparent in recent years. Here, we summ...

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Detalles Bibliográficos
Autores principales: Xu, Huiyun, Duan, Jing, Ning, Dandan, Li, Jingbao, Liu, Ruofei, Yang, Ruixin, Jiang, Jean X., Shang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2014
Materias:
Contributed Mini Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345510/
https://www.ncbi.nlm.nih.gov/pubmed/25301020
http://dx.doi.org/10.5483/BMBRep.2014.47.12.193
Descripción
Sumario:The Wnt signaling pathway is well known to play major roles in skeletal development and homeostasis. In certain aspects, fracture repair mimics the process of bone embryonic development. Thus, the importance of Wnt signaling in fracture healing has become more apparent in recent years. Here, we summarize recent research progress in the area, which may be conducive to the development of Wnt-based therapeutic strategies for bone repair. [BMB Reports 2014; 47(12): 666-672]

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