Role of Wnt signaling in fracture healing

The Wnt signaling pathway is well known to play major roles in skeletal development and homeostasis. In certain aspects, fracture repair mimics the process of bone embryonic development. Thus, the importance of Wnt signaling in fracture healing has become more apparent in recent years. Here, we summ...

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Autores principales: Xu, Huiyun, Duan, Jing, Ning, Dandan, Li, Jingbao, Liu, Ruofei, Yang, Ruixin, Jiang, Jean X., Shang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2014
Materias:
Contributed Mini Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345510/
https://www.ncbi.nlm.nih.gov/pubmed/25301020
http://dx.doi.org/10.5483/BMBRep.2014.47.12.193
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author Xu, Huiyun
Duan, Jing
Ning, Dandan
Li, Jingbao
Liu, Ruofei
Yang, Ruixin
Jiang, Jean X.
Shang, Peng
author_facet Xu, Huiyun
Duan, Jing
Ning, Dandan
Li, Jingbao
Liu, Ruofei
Yang, Ruixin
Jiang, Jean X.
Shang, Peng
author_sort Xu, Huiyun
collection PubMed
description The Wnt signaling pathway is well known to play major roles in skeletal development and homeostasis. In certain aspects, fracture repair mimics the process of bone embryonic development. Thus, the importance of Wnt signaling in fracture healing has become more apparent in recent years. Here, we summarize recent research progress in the area, which may be conducive to the development of Wnt-based therapeutic strategies for bone repair. [BMB Reports 2014; 47(12): 666-672]
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spelling pubmed-43455102015-03-02 Role of Wnt signaling in fracture healing Xu, Huiyun Duan, Jing Ning, Dandan Li, Jingbao Liu, Ruofei Yang, Ruixin Jiang, Jean X. Shang, Peng BMB Rep Contributed Mini Review The Wnt signaling pathway is well known to play major roles in skeletal development and homeostasis. In certain aspects, fracture repair mimics the process of bone embryonic development. Thus, the importance of Wnt signaling in fracture healing has become more apparent in recent years. Here, we summarize recent research progress in the area, which may be conducive to the development of Wnt-based therapeutic strategies for bone repair. [BMB Reports 2014; 47(12): 666-672] Korean Society for Biochemistry and Molecular Biology 2014-12 /pmc/articles/PMC4345510/ /pubmed/25301020 http://dx.doi.org/10.5483/BMBRep.2014.47.12.193 Text en Copyright © 2014, Korean Society for Biochemistry and Molecular Biology http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Contributed Mini Review
Xu, Huiyun
Duan, Jing
Ning, Dandan
Li, Jingbao
Liu, Ruofei
Yang, Ruixin
Jiang, Jean X.
Shang, Peng
Role of Wnt signaling in fracture healing
title Role of Wnt signaling in fracture healing
title_full Role of Wnt signaling in fracture healing
title_fullStr Role of Wnt signaling in fracture healing
title_full_unstemmed Role of Wnt signaling in fracture healing
title_short Role of Wnt signaling in fracture healing
title_sort role of wnt signaling in fracture healing
topic Contributed Mini Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345510/
https://www.ncbi.nlm.nih.gov/pubmed/25301020
http://dx.doi.org/10.5483/BMBRep.2014.47.12.193
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