Constitutively active Ras negatively regulates Erk MAP kinase through induction of MAP kinase phosphatase 3 (MKP3) in NIH3T3 cells

The Ras/Raf/MEK/Erk signaling pathway is important for regulation of cell growth, proliferation, differentiation, survival, and apoptosis in response to a variety of extracellular stimuli. Lack of Erk MAPK activation is observed in several cancer cells despite active activation of Ras. However, litt...

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Detalles Bibliográficos
Autores principales: Park, Young Jae, Lee, Jong Min, Shin, Soon Young, Kim, Young Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2014
Materias:
Research-Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345513/
https://www.ncbi.nlm.nih.gov/pubmed/24602610
http://dx.doi.org/10.5483/BMBRep.2014.47.12.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345513/
https://www.ncbi.nlm.nih.gov/pubmed/24602610
http://dx.doi.org/10.5483/BMBRep.2014.47.12.017

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