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SURGICAL MANAGEMENT OF INFECTED THORACIC ANEURYSMS

Infected thoracic aortic aneurysm (ITAA) is a relatively rare disease. The diagnosis of ITAA is generally made comprehensively based on symptoms, laboratory data and CT findings. Several series of blood cultures are mandatory to first detect the infecting organism. ITAA is usually suspected as a res...

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Autor principal: USUI, AKIHIKO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nagoya University 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345670/
https://www.ncbi.nlm.nih.gov/pubmed/24640172
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author USUI, AKIHIKO
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description Infected thoracic aortic aneurysm (ITAA) is a relatively rare disease. The diagnosis of ITAA is generally made comprehensively based on symptoms, laboratory data and CT findings. Several series of blood cultures are mandatory to first detect the infecting organism. ITAA is usually suspected as a result of the CT findings. A short-interval CT re-examination is essential to confirm the correct diagnosis. A CT scan commonly demonstrates a rapid enlargement of the aneurismal lumen and soft tissue mass surrounding the aorta. One of the characteristics of ITAA is the presence of several nodular or saccular aneurysms localized in different aortic portions. Patients with ITAA are associated with high incidences of aneurismal rupture due to the aneurysm’s abrupt growth. Therefore, ITAAs are associated with both high morbidities and mortalities. The major concerns regarding surgical treatment for ITAA are the control of infection, the resection of whole infected tissue, grafting via an aseptic route and the prevention of recrudescent infection. Therefore, effectual antibiotic therapy is mandatory as the first choice of therapy. Ideally surgical intervention is indicated in patients with a controlled infection. It is essential to excise the whole infected aneurysm and to reconstruct in-situ grafting via an aseptic route. However, urgent surgery is often required in patients with an uncontrolled infection because they have an impending aneurismal rupture. In such cases, an extra-anatomical bypass without cardiopulmonary bypass is applicable. Surgical strategies should therefore be determined on a case-by-case basis because these patients present various clinical courses.
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spelling pubmed-43456702015-03-04 SURGICAL MANAGEMENT OF INFECTED THORACIC ANEURYSMS USUI, AKIHIKO Nagoya J Med Sci Invited Review Article Infected thoracic aortic aneurysm (ITAA) is a relatively rare disease. The diagnosis of ITAA is generally made comprehensively based on symptoms, laboratory data and CT findings. Several series of blood cultures are mandatory to first detect the infecting organism. ITAA is usually suspected as a result of the CT findings. A short-interval CT re-examination is essential to confirm the correct diagnosis. A CT scan commonly demonstrates a rapid enlargement of the aneurismal lumen and soft tissue mass surrounding the aorta. One of the characteristics of ITAA is the presence of several nodular or saccular aneurysms localized in different aortic portions. Patients with ITAA are associated with high incidences of aneurismal rupture due to the aneurysm’s abrupt growth. Therefore, ITAAs are associated with both high morbidities and mortalities. The major concerns regarding surgical treatment for ITAA are the control of infection, the resection of whole infected tissue, grafting via an aseptic route and the prevention of recrudescent infection. Therefore, effectual antibiotic therapy is mandatory as the first choice of therapy. Ideally surgical intervention is indicated in patients with a controlled infection. It is essential to excise the whole infected aneurysm and to reconstruct in-situ grafting via an aseptic route. However, urgent surgery is often required in patients with an uncontrolled infection because they have an impending aneurismal rupture. In such cases, an extra-anatomical bypass without cardiopulmonary bypass is applicable. Surgical strategies should therefore be determined on a case-by-case basis because these patients present various clinical courses. Nagoya University 2013-08 /pmc/articles/PMC4345670/ /pubmed/24640172 Text en http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Invited Review Article
USUI, AKIHIKO
SURGICAL MANAGEMENT OF INFECTED THORACIC ANEURYSMS
title SURGICAL MANAGEMENT OF INFECTED THORACIC ANEURYSMS
title_full SURGICAL MANAGEMENT OF INFECTED THORACIC ANEURYSMS
title_fullStr SURGICAL MANAGEMENT OF INFECTED THORACIC ANEURYSMS
title_full_unstemmed SURGICAL MANAGEMENT OF INFECTED THORACIC ANEURYSMS
title_short SURGICAL MANAGEMENT OF INFECTED THORACIC ANEURYSMS
title_sort surgical management of infected thoracic aneurysms
topic Invited Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345670/
https://www.ncbi.nlm.nih.gov/pubmed/24640172
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