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ATHEROTHROMBOTIC LESION OF THE MIDDLE CEREBRAL ARTERY: REPORT OF 21 CASES WITH STENOTIC AND OBSTRUCTIVE LESIONS

This was a retrospective analysis of 12 consecutive cases of middle cerebral artery stenosis and 9 consecutive cases of middle cerebral artery occlusion that presented to our hospital with acute cerebral ischemia. The degree and area of the cerebral infarctions were assessed with the Alberta Stroke...

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Autores principales: OYAMA, HIROFUMI, KITO, AKIRA, MAKI, HIDEKI, HATTORI, KENICHI, NODA, TOMOYUKI, WADA, KENTARO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nagoya University 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345696/
https://www.ncbi.nlm.nih.gov/pubmed/23544267
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author OYAMA, HIROFUMI
KITO, AKIRA
MAKI, HIDEKI
HATTORI, KENICHI
NODA, TOMOYUKI
WADA, KENTARO
author_facet OYAMA, HIROFUMI
KITO, AKIRA
MAKI, HIDEKI
HATTORI, KENICHI
NODA, TOMOYUKI
WADA, KENTARO
author_sort OYAMA, HIROFUMI
collection PubMed
description This was a retrospective analysis of 12 consecutive cases of middle cerebral artery stenosis and 9 consecutive cases of middle cerebral artery occlusion that presented to our hospital with acute cerebral ischemia. The degree and area of the cerebral infarctions were assessed with the Alberta Stroke Program Early CT Score (ASPECTS) and ASPECTS-DWI (APSECTS with assessment of white matter lesion using diffusion-weighted image). As for cerebral infarctions in the region of the perforating artery, lesions that were more than 20 mm long in the caudal-cranial direction were diagnosed as branch atheromatous disease (BAD). Activities of daily living (ADL) were poorer in the cases with lower ASPECTS and ASPECTS-DWI. ADL tended to be worse in cases with BAD than in those without. The prognosis was significantly poorer in the group with ASPECTS≤7 points. ASPECTS tended to be lower in cases with BAD than in those without. ADL, ASPECTS and the presence of BAD were not significantly different between the stenosis and obstruction groups. In summary, the neurological prognosis was dependent on the extent of the cerebral infarction and was related to BAD to some extent. These findings will be important when considering medical treatment at the outpatient clinic setting.
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spelling pubmed-43456962015-03-04 ATHEROTHROMBOTIC LESION OF THE MIDDLE CEREBRAL ARTERY: REPORT OF 21 CASES WITH STENOTIC AND OBSTRUCTIVE LESIONS OYAMA, HIROFUMI KITO, AKIRA MAKI, HIDEKI HATTORI, KENICHI NODA, TOMOYUKI WADA, KENTARO Nagoya J Med Sci Original Paper This was a retrospective analysis of 12 consecutive cases of middle cerebral artery stenosis and 9 consecutive cases of middle cerebral artery occlusion that presented to our hospital with acute cerebral ischemia. The degree and area of the cerebral infarctions were assessed with the Alberta Stroke Program Early CT Score (ASPECTS) and ASPECTS-DWI (APSECTS with assessment of white matter lesion using diffusion-weighted image). As for cerebral infarctions in the region of the perforating artery, lesions that were more than 20 mm long in the caudal-cranial direction were diagnosed as branch atheromatous disease (BAD). Activities of daily living (ADL) were poorer in the cases with lower ASPECTS and ASPECTS-DWI. ADL tended to be worse in cases with BAD than in those without. The prognosis was significantly poorer in the group with ASPECTS≤7 points. ASPECTS tended to be lower in cases with BAD than in those without. ADL, ASPECTS and the presence of BAD were not significantly different between the stenosis and obstruction groups. In summary, the neurological prognosis was dependent on the extent of the cerebral infarction and was related to BAD to some extent. These findings will be important when considering medical treatment at the outpatient clinic setting. Nagoya University 2013-02 /pmc/articles/PMC4345696/ /pubmed/23544267 Text en http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Paper
OYAMA, HIROFUMI
KITO, AKIRA
MAKI, HIDEKI
HATTORI, KENICHI
NODA, TOMOYUKI
WADA, KENTARO
ATHEROTHROMBOTIC LESION OF THE MIDDLE CEREBRAL ARTERY: REPORT OF 21 CASES WITH STENOTIC AND OBSTRUCTIVE LESIONS
title ATHEROTHROMBOTIC LESION OF THE MIDDLE CEREBRAL ARTERY: REPORT OF 21 CASES WITH STENOTIC AND OBSTRUCTIVE LESIONS
title_full ATHEROTHROMBOTIC LESION OF THE MIDDLE CEREBRAL ARTERY: REPORT OF 21 CASES WITH STENOTIC AND OBSTRUCTIVE LESIONS
title_fullStr ATHEROTHROMBOTIC LESION OF THE MIDDLE CEREBRAL ARTERY: REPORT OF 21 CASES WITH STENOTIC AND OBSTRUCTIVE LESIONS
title_full_unstemmed ATHEROTHROMBOTIC LESION OF THE MIDDLE CEREBRAL ARTERY: REPORT OF 21 CASES WITH STENOTIC AND OBSTRUCTIVE LESIONS
title_short ATHEROTHROMBOTIC LESION OF THE MIDDLE CEREBRAL ARTERY: REPORT OF 21 CASES WITH STENOTIC AND OBSTRUCTIVE LESIONS
title_sort atherothrombotic lesion of the middle cerebral artery: report of 21 cases with stenotic and obstructive lesions
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345696/
https://www.ncbi.nlm.nih.gov/pubmed/23544267
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