Cargando…

CEREBRAL HEMORRHAGE AND CEREBRAL INFARCTION IN 30 CASES OF ADULT MOYAMOYA DISEASE: COMPARISON BETWEEN CONSERVATIVE THERAPY AND SUPERFICIAL TEMPORAL ARTERY-MIDDLE CEREBRAL ARTERY ANASTOMOSIS

To clarify the effect of surgery on the prevention cerebral hemorrhage in adult moyamoya disease, we compared postoperative courses between superficial temporal artery-middle cerebral artery (STA-MCA) anastomosis and conservative therapy. The study subjects were 30 adults with moyamoya disease. Unil...

Descripción completa

Detalles Bibliográficos
Autores principales: OYAMA, HIROFUMI, KITO, AKIRA, MAKI, HIDEKI, HATTORI, KENICHI, NODA, TOMOYUKI, WADA, KENTARO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nagoya University 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345700/
https://www.ncbi.nlm.nih.gov/pubmed/23544266
_version_ 1782359610232930304
author OYAMA, HIROFUMI
KITO, AKIRA
MAKI, HIDEKI
HATTORI, KENICHI
NODA, TOMOYUKI
WADA, KENTARO
author_facet OYAMA, HIROFUMI
KITO, AKIRA
MAKI, HIDEKI
HATTORI, KENICHI
NODA, TOMOYUKI
WADA, KENTARO
author_sort OYAMA, HIROFUMI
collection PubMed
description To clarify the effect of surgery on the prevention cerebral hemorrhage in adult moyamoya disease, we compared postoperative courses between superficial temporal artery-middle cerebral artery (STA-MCA) anastomosis and conservative therapy. The study subjects were 30 adults with moyamoya disease. Unilateral STA-MCA anastomosis was conducted in 7 of these 30 cases, and bilateral STA-MCA anastomosis was conducted in 8 of these 30 cases. Therefore, anastomosis was performed in a total of 23 sides. The postoperative clinical course was observed for more than 5 years after the STA-MCA anastomosis. Cerebral hemorrhage occurred after operation in 2 sides (8.7%) among the 23 sides that received STA-MCA anastomosis. On the contrary, hemorrhage occurred during conservative therapy in 5 sides (13.5%) among 37 non-operation sides (no significance in χ2 test). Cerebral infarction occurred in 3 sides (13%) among 23 sides treated with STA-MCA anastomosis. However, the infarction occurred in 2 sides (5.4%) among the 37 non-operation sides (no significance in χ2 test). Cerebral hemorrhage tended to occur less frequently after STA-MCA anastomosis, and bypass surgery was suggested to have some beneficial effect in preventing cerebral hemorrhage in adult moyamoya disease. However, it was revealed that STA-MCA anastomosis exacerbated the brain ischemia. Therefore, strict management is mandatory in the perioperative period.
format Online
Article
Text
id pubmed-4345700
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Nagoya University
record_format MEDLINE/PubMed
spelling pubmed-43457002015-03-04 CEREBRAL HEMORRHAGE AND CEREBRAL INFARCTION IN 30 CASES OF ADULT MOYAMOYA DISEASE: COMPARISON BETWEEN CONSERVATIVE THERAPY AND SUPERFICIAL TEMPORAL ARTERY-MIDDLE CEREBRAL ARTERY ANASTOMOSIS OYAMA, HIROFUMI KITO, AKIRA MAKI, HIDEKI HATTORI, KENICHI NODA, TOMOYUKI WADA, KENTARO Nagoya J Med Sci Original Paper To clarify the effect of surgery on the prevention cerebral hemorrhage in adult moyamoya disease, we compared postoperative courses between superficial temporal artery-middle cerebral artery (STA-MCA) anastomosis and conservative therapy. The study subjects were 30 adults with moyamoya disease. Unilateral STA-MCA anastomosis was conducted in 7 of these 30 cases, and bilateral STA-MCA anastomosis was conducted in 8 of these 30 cases. Therefore, anastomosis was performed in a total of 23 sides. The postoperative clinical course was observed for more than 5 years after the STA-MCA anastomosis. Cerebral hemorrhage occurred after operation in 2 sides (8.7%) among the 23 sides that received STA-MCA anastomosis. On the contrary, hemorrhage occurred during conservative therapy in 5 sides (13.5%) among 37 non-operation sides (no significance in χ2 test). Cerebral infarction occurred in 3 sides (13%) among 23 sides treated with STA-MCA anastomosis. However, the infarction occurred in 2 sides (5.4%) among the 37 non-operation sides (no significance in χ2 test). Cerebral hemorrhage tended to occur less frequently after STA-MCA anastomosis, and bypass surgery was suggested to have some beneficial effect in preventing cerebral hemorrhage in adult moyamoya disease. However, it was revealed that STA-MCA anastomosis exacerbated the brain ischemia. Therefore, strict management is mandatory in the perioperative period. Nagoya University 2013-02 /pmc/articles/PMC4345700/ /pubmed/23544266 Text en http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Paper
OYAMA, HIROFUMI
KITO, AKIRA
MAKI, HIDEKI
HATTORI, KENICHI
NODA, TOMOYUKI
WADA, KENTARO
CEREBRAL HEMORRHAGE AND CEREBRAL INFARCTION IN 30 CASES OF ADULT MOYAMOYA DISEASE: COMPARISON BETWEEN CONSERVATIVE THERAPY AND SUPERFICIAL TEMPORAL ARTERY-MIDDLE CEREBRAL ARTERY ANASTOMOSIS
title CEREBRAL HEMORRHAGE AND CEREBRAL INFARCTION IN 30 CASES OF ADULT MOYAMOYA DISEASE: COMPARISON BETWEEN CONSERVATIVE THERAPY AND SUPERFICIAL TEMPORAL ARTERY-MIDDLE CEREBRAL ARTERY ANASTOMOSIS
title_full CEREBRAL HEMORRHAGE AND CEREBRAL INFARCTION IN 30 CASES OF ADULT MOYAMOYA DISEASE: COMPARISON BETWEEN CONSERVATIVE THERAPY AND SUPERFICIAL TEMPORAL ARTERY-MIDDLE CEREBRAL ARTERY ANASTOMOSIS
title_fullStr CEREBRAL HEMORRHAGE AND CEREBRAL INFARCTION IN 30 CASES OF ADULT MOYAMOYA DISEASE: COMPARISON BETWEEN CONSERVATIVE THERAPY AND SUPERFICIAL TEMPORAL ARTERY-MIDDLE CEREBRAL ARTERY ANASTOMOSIS
title_full_unstemmed CEREBRAL HEMORRHAGE AND CEREBRAL INFARCTION IN 30 CASES OF ADULT MOYAMOYA DISEASE: COMPARISON BETWEEN CONSERVATIVE THERAPY AND SUPERFICIAL TEMPORAL ARTERY-MIDDLE CEREBRAL ARTERY ANASTOMOSIS
title_short CEREBRAL HEMORRHAGE AND CEREBRAL INFARCTION IN 30 CASES OF ADULT MOYAMOYA DISEASE: COMPARISON BETWEEN CONSERVATIVE THERAPY AND SUPERFICIAL TEMPORAL ARTERY-MIDDLE CEREBRAL ARTERY ANASTOMOSIS
title_sort cerebral hemorrhage and cerebral infarction in 30 cases of adult moyamoya disease: comparison between conservative therapy and superficial temporal artery-middle cerebral artery anastomosis
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345700/
https://www.ncbi.nlm.nih.gov/pubmed/23544266
work_keys_str_mv AT oyamahirofumi cerebralhemorrhageandcerebralinfarctionin30casesofadultmoyamoyadiseasecomparisonbetweenconservativetherapyandsuperficialtemporalarterymiddlecerebralarteryanastomosis
AT kitoakira cerebralhemorrhageandcerebralinfarctionin30casesofadultmoyamoyadiseasecomparisonbetweenconservativetherapyandsuperficialtemporalarterymiddlecerebralarteryanastomosis
AT makihideki cerebralhemorrhageandcerebralinfarctionin30casesofadultmoyamoyadiseasecomparisonbetweenconservativetherapyandsuperficialtemporalarterymiddlecerebralarteryanastomosis
AT hattorikenichi cerebralhemorrhageandcerebralinfarctionin30casesofadultmoyamoyadiseasecomparisonbetweenconservativetherapyandsuperficialtemporalarterymiddlecerebralarteryanastomosis
AT nodatomoyuki cerebralhemorrhageandcerebralinfarctionin30casesofadultmoyamoyadiseasecomparisonbetweenconservativetherapyandsuperficialtemporalarterymiddlecerebralarteryanastomosis
AT wadakentaro cerebralhemorrhageandcerebralinfarctionin30casesofadultmoyamoyadiseasecomparisonbetweenconservativetherapyandsuperficialtemporalarterymiddlecerebralarteryanastomosis