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Inhalation therapy with the synthetic TIP-like peptide AP318 attenuates pulmonary inflammation in a porcine sepsis model

BACKGROUND: The lectin-like domain of TNF-α can be mimicked by synthetic TIP peptides and represents an innovative pharmacologic option to treat edematous respiratory failure. TIP inhalation was shown to reduce pulmonary edema and improve gas exchange. In addition to its edema resolution effect, TIP...

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Detalles Bibliográficos
Autores principales: Hartmann, Erik K, Ziebart, Alexander, Thomas, Rainer, Liu, Tanghua, Schad, Arno, Tews, Martha, Moosmann, Bernd, Kamuf, Jens, Duenges, Bastian, Thal, Serge C, David, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346123/
https://www.ncbi.nlm.nih.gov/pubmed/25879802
http://dx.doi.org/10.1186/s12890-015-0002-6

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