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Human mesenchymal stem/stromal cells suppress spinal inflammation in mice with contribution of pituitary adenylate cyclase-activating polypeptide (PACAP)

BACKGROUND: Adult human mesenchymal stem/stromal cells (hMSCs) from bone marrow have been reported to exhibit beneficial effects on spinal cord injury (SCI). A neuropeptide, pituitary adenylate cyclase-activating polypeptide (PACAP) is known to decrease neuronal cell death and inflammatory response...

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Detalles Bibliográficos
Autores principales: Tsumuraya, Tomomi, Ohtaki, Hirokazu, Song, Dandan, Sato, Atsushi, Watanabe, Jun, Hiraizumi, Yutaka, Nakamachi, Tomoya, Xu, Zhifang, Dohi, Kenji, Hashimoto, Hitoshi, Atsumi, Takashi, Shioda, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346126/
https://www.ncbi.nlm.nih.gov/pubmed/25889720
http://dx.doi.org/10.1186/s12974-015-0252-5