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Generation of cellular immune memory and B-cell immunity are impaired by natural killer cells
The goal of most vaccines is the induction of long-lived memory T and B cells capable of protecting the host from infection by cytotoxic mechanisms, cytokines and high-affinity antibodies. However, efforts to develop vaccines against major human pathogens like HIV and HCV have not been successful, t...
Autores principales: | Rydyznski, Carolyn, Daniels, Keith A., Karmele, Erik P., Brooks, Taylor R., Mahl, Sarah E., Moran, Michael T., Li, Caimei, Sutiwisesak, Rujapak, Welsh, Raymond M., Waggoner, Stephen N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346304/ https://www.ncbi.nlm.nih.gov/pubmed/25721802 http://dx.doi.org/10.1038/ncomms7375 |
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